Our rankings are cleverly generated from the algorithmic analysis of thousands of customer reviews about products, brands, merchant’s customer service levels, popularity trends, and more. The rankings reflect our opinion and should be a good starting point for shopping. By purchasing the products we rank, you’ll get the lowest price we found while we may receive a commission at no cost to you, which will help us continue to provide you with value.
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Flea Tick Controls of 2025
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- Best Choice
1
FrontlineFRONTLINE Plus for Dogs Flea and Tick Treatment (Large Dog, 45-88 lbs.) 3 Doses (Purple Box)
11% OffMain highlights-
Comprehensive Flea and Tick Protection
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Ideal for Large Dogs
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Waterproof and Long-lasting
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How do we rank?
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- Value for Money
2
FrontlineFrontline Plus Flea and Tick Treatment for Medium Dogs Up to 23 to 44 lbs. 3 Treatments
11% OffMain highlights-
Long-Lasting Protection
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Ideal for Active Dogs
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Odorless and Quick-Drying
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3
PetArmorPetArmor Plus Flea and Tick Prevention for Dogs, Dog Flea and Tick Treatment, 3 Doses, Waterproof Topical, Fast Acting, Large Dogs (45-88 lbs)
14% OffMain highlights-
Powerful Flea and Tick Protection
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Ideal for Large Dogs 45-88 lbs
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Ease of Use Praised by Customers
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4
WondercideWondercide - Flea, Tick & Mosquito Spray for Pets and Home with Natural Essential Oils - Killer, Control, Prevention, Treatment - Lemongrass 16 oz
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Natural Essential Oils Protection
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Ideal for Pets and Home Use
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Praised for Pleasant Scent and Effectiveness
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See Today’s Deals & Prices
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WondercideWondercide - Ready to Use Flea, Tick, and Mosquito Yard Spray with Natural Essential Oils – Mosquito and Insect Killer, Treatment, and Repellent - Plant-Based - Safe Around Pets, Plants, Kids - 32 oz
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Pet_Friendly_Solution
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FrontlineFrontline Plus Flea and Tick Treatment for Cats Over 1.5 lbs. 3 Treatments
11% OffMain highlights-
Waterproof Long-Lasting Protection
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Ideal for Infestation Prevention
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Veterinarian Trusted
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BugMDBugMD Flea and Tick Concentrate (3.7 oz, 2 Pack) - Essential Oil-Powered Formula, Controls Fleas, Ticks, Mites in Dogs and Other Furred Animals, Spray on Pet Beds, Kennels
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FrontlineFrontline Plus Flea and Tick Treatment for Small Dogs Upto 5 to 22 lbs. 3 Treatments
11% OffMain highlights-
Long-Lasting Protection
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Ideal for Small Dogs
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Highly Effective
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TevraPetTevraPet Activate II Flea and Tick Prevention for Dogs | 4 Count | Extra Large Dogs 55+ lbs | Topical Drops | 4 Months Flea Treatment
Main highlights-
Fast Acting Flea and Tick Protection
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Ideal for Large Dogs
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Easy Application Praised by Users
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Similar products on Amazon
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Veterinary Formula Flea and Tick Spray for Dogs, 8 oz – Easy-to-Use Dog Flea Spray, Kills on Contact, Prevents Egg & Larval Development for 14 weeks
KILLS FLEAS AND TICKS ON CONTACT – Veterinary Formula 8 oz. Flea and Tick Spray for Dogs eliminates fleas and ticks at all stages: egg, larval, and adult. Treatment also prevents future egg and larvae development$9.12
- 23% OffFree Shipping
Ortho BugClear Lawn Insect Killer1, Kills Ants, Spiders, Ticks, Fleas, Armyworms and Grubs, Treats up to 16,500 sq. ft., 10 lb.
Ortho BugClear Lawn Insect Killer1 kills listed insects by contact, including ants, spiders, ticks, fleas, grubs, beetles and armyworms$9.58
$12.49 (23% Off) - 10% OffFree Shipping
PETARMOR Home Carpet Powder for Fleas and Ticks, Protect Your Home From Fleas and Deodorizes Carpets, 16 Ounce
LONG-LASTING CONTROL: PETARMOR Home & Carpet Powder kills fleas, brown dog ticks, flea eggs, flea larvae, and flea pupae.$8.99
$9.99 (10% Off) - 37% OffFree Shipping
Chewable Flea and Tick Prevention for Dogs - 120 Soft Chews Made in USA - Oral Flea and Tick Control Pills for Small, Medium, Large Dogs and Puppies - Skin and Coat Supplement Treats for All Breeds
Bite-Sized Protection, Big-Time Benefits: soft chews offer daily flea and tick prevention for dogs, and flea & tick control—all in one tasty treat. Say goodbye to mess and hello to dependable, chewable protection your pup will love.$24.99
$39.99 (37% Off) - 21% OffFree Shipping
Flea and Tick Prevention for Dogs Chewables -Made in USA- Natural Dog Flea and Tick Treatment - Oral Flea Pills - Vet Recommended Flea and Tick Chews - All Breeds & Sizes - 120 Soft Treats (Chicken)
Flea And Tick Prevention For Dogs: Natural essentials your dog needs in a perfectly balanced formula to boost skin, coat & immune health and prevent fleas & ticks from laying eggs on your dog’s coat.$21.95
$27.99 (21% Off) - Free Shipping
Amazon Basics Flea and Tick Topical Treatment for Cats (Over 1.5 Pounds), 6 Count (Previously Solimo)
Same product, new look―This product is identical in manufacturing and formulation as the Solimo brand$21.59
- Free Shipping
K9 Advantix II XL Dog Vet-Recommended Flea, Tick & Mosquito Treatment & Prevention | Dogs Over 55 lbs. | 1-Mo Supply
K9 Advantix II Extra Large Dog 30-day treatment & prevention protects dogs over 55 lbs. from fleas, ticks, mosquitoes, biting flies and lice$18.98