Sinus Medicines of 2025
- Best Choice
1
Clicked 158 times in the last monthGenCareGenCare - Nasal Decongestant (10mg Tablets) Phenylephrine HCl (300 Tablets Per Bottle) | Value Pack Non Drowsy Sinus and Nasal Congestion Relief | Lower Sinus Pressure Due to Allergies or Illness
9.7 worth the money9.5 dispense easily9.3 simple to consumeWhy we love it
Effective non-drowsy decongestant.
Convenient bulk savings bottle.
Easy to find online.
- Curious about how we select the top products for you? Explore How It Works
- Value for Money
2
VicksVicks Sinex SEVERE Nasal Spray, Original Ultra Fine Mist, Decongestant Medicine, Relief from Stuffy Nose due to Cold or Allergy, & Nasal Congestion, Sinus Pressure Relief, 265 Sprays x 2
9.5 Simple to use9.3 Moisturizing9.1 worth the moneyWhy we love it
Long-lasting 12-hour relief.
Direct application to nasal membranes.
Highly effective for severe congestion.
3
MucinexMucinex Sinus Max Severe Congestion & Pain Relief, Maximum Strength Nasal & Sinus Relief, Decongestant for Adults, Acetaminophen Pain Reliever, Guaifenesin Expectorant and Mucus Removal, 20 Caplets
Why we love it
Effective relief for multiple congestion types.
Trusted brand by doctors.
Compact packaging for easy use.
4
AdvilAdvil Sinus Congestion and Pain, Sinus Relief Medicine, Pain Reliever and Fever Reducer with Ibuprofen and Phenylephrine HCl - 20 Coated Tablets
9.7 pain management9.3 simple to consume8.0 Packaging materialsWhy we love it
Effective for sinus and headache relief.
Convenient single-tablet dosing.
Portable for easy, anytime relief.
5
VicksVicks Sinex SEVERE, All-In-One Sinus + Mucus Relief, Non-Drowsy, Loosens Mucus, Maximum Strength Relief of Pain, Pressure, Congestion, & Headache Relief, 24 LiquiCaps
Why we love it
Non-drowsy formula for daytime use.
Targets multiple sinus symptoms effectively.
Highly rated by users for quick relief.
6
SudafedSudafed PE Sinus Congestion Day + Night Maximum Strength Decongestant & Antihistamine Tablets with Phenylephrine HCl & Diphenhydramine HCl, Helps Nasal & Sinus Pressure & Congestion, 20 ct
9.5 simple to consume8.7 worth the money8.4 pain managementWhy we love it
Effective day and night relief.
Includes antihistamine for nighttime symptoms.
Highly recommended by users.
7
SudafedSudafed PE Head Congestion + Mucus Tablets for Sinus Pressure, Pain & Congestion, 24 ct
9.9 simple to consume9.7 pain management8.0 For Gentle skinWhy we love it
Non-drowsy formula ensures daytime use.
Effective for sinus and chest congestion.
Highly recommended for stuffy nose relief.
8
BoironBoiron SinusCalm Tablets for Sinus Pain Relief, Runny Nose, Congestion, Sinus Pressure, Headache - 60 Count
9.3 simple to consume8.2 Flavor8.0 worth the moneyWhy we love it
Non-drowsy formula.
Easy to use for all ages.
Effective for runny nose.
9
ALKA-SELTZER PLUSAlka-Seltzer Plus Maximum Strength Power Max Sinus, Allergy and Cough Medicine for Adults and Children 12 Years and Older - Relieves Symptoms from Allergies, Colds or Hay Fever, 24 Count
9.3 Flavor9.3 worth the money9.1 simple to consumeWhy we love it
Effective relief for allergies and colds.
Includes pain reliever and fever reducer.
Works quickly for fast symptom relief.
10
Rite AidRite Aid Daytime Severe Sinus Congestion & Pain Relief - Acetaminophen, 325 mg - 24 Caplets | Multi-Symptom Non-Drowsy | Relief | Cold and Flu | Cold & Sinus Medicine for Adults
9.9 pain management9.7 worth the money9.3 simple to consumeWhy we love it
Effective multi-symptom relief.
Non-drowsy daytime formula.
Affordable alternative to name brands.