July 1, 2025

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Sinus Medicines of 2025

Save up to 23% off

Best Choice

1

Mucinex
Mucinex Sinus-Max Day Pressure, Pain & Cough & Nightshift Night Sinus Medicine for Adults, Day/Night Combo Pack for Sore Throat Relief, Nasal Congestion Relief, Cough & Cold Medicines, 40 Caplets

20% Off
Main highlights

Powerful Multi-Symptom Relief
Mucinex Maximum Strength Sinus-Max provides fast relief from sinus pressure, pain, cough, and congestion.

Ideal for Severe Allergy Season
Perfect for managing severe pollen allergies and seasonal cold symptoms effectively.

Highly Effective Symptom Control
Praised for its effectiveness in reducing allergy symptoms and congestion.
9.6

Exceptional

Our Rating

9.3
simple to consume

8.9
worth the money
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Careful review Our team ensures quality, value, and fit based on real user feedback

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Real users impact

Thousands of users trust our site daily

Based on millions of stores and reviews

Shoppers influence our rankings
Analyzing top stores
Value for Money

2

Advil
Advil Sinus Congestion and Pain, Sinus Relief Medicine, Pain Reliever and Fever Reducer with Ibuprofen and Phenylephrine HCl - 20 Coated Tablets
Main highlights

Comprehensive Sinus Relief
Combines ibuprofen and phenylephrine for pain, fever, and sinus congestion relief.

Portable and Convenient
Ideal for on-the-go relief; easily fits in bags or pockets.

Quick and Effective Performance
Praised for rapid relief of sinus congestion and headaches.
9.4

Excellent

Our Rating

9.7
pain management

9.3
simple to consume

8.0
Packaging materials
3

Mucinex
Mucinex Sinus-Max Severe Congestion Relief Caplets, 20 Count

21% Off
Main highlights

Maximum Strength Relief
Provides relief from pain, headache, nasal, sinus, and chest congestion.

Ideal for Severe Congestion
Best for adults experiencing severe sinus and nasal congestion.

Praised for Effectiveness
Customers appreciate the product's good results despite small packaging.
9.2

Excellent

Our Rating
4

GenCare
GenCare - Nasal Decongestant (10mg Tablets) Phenylephrine HCl (300 Tablets Per Bottle) | Value Pack Non Drowsy Sinus and Nasal Congestion Relief | Lower Sinus Pressure Due to Allergies or Illness

16% Off
Main highlights

Maximum Strength Relief
10 mg Phenylephrine HCl provides strong sinus and nasal congestion relief.

Ideal for Chronic Congestion
Perfect for families or individuals with frequent allergy symptoms.

Highly Praised Value
Customers appreciate the affordability and effectiveness compared to other brands.
9.0

Excellent

Our Rating

9.7
worth the money

9.5
dispense easily

9.3
simple to consume
5

Sudafed
Sudafed PE Head Congestion + Mucus Tablets for Sinus Pressure, Pain & Congestion, 24 ct

12% Off
Main highlights

Comprehensive Relief
Provides non-drowsy relief from sinus pain, pressure, and congestion with acetaminophen, phenylephrine HCl, and guaifenesin.

Ideal for Cold and Allergy Symptoms
Perfect for alleviating symptoms of hay fever, upper respiratory allergies, and the common cold.

Highly Effective for Stuffy Nose
Praised for its effectiveness in relieving stuffy noses, according to customer reviews.
8.9

Very Good

Our Rating

9.9
simple to consume

9.7
pain management

8.0
For Gentle skin
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6

Vicks
Vicks Sinex SEVERE Allergy & Sinus Nasal Spray, Original Ultra Fine Mist, Decongestant Medicine, Relief from Nasal Congestion due to Cold or Allergy, Sinus Pressure Relief, 265 Sprays x 2

14% Off
Main highlights

12-Hour Relief from Congestion
Provides instant, long-lasting relief from nasal congestion and sinus pressure for up to 12 hours.

Ideal for Cold and Allergy Season
Perfect for treating severe sinus congestion and pressure from colds or allergies.

Instant Effectiveness Praised by Users
Highly rated for its immediate effectiveness in clearing nasal passages.
8.7

Very Good

Our Rating

9.5
Simple to use

9.3
Moisturizing

9.1
worth the money
7

Boiron
Boiron SinusCalm Tablets for Sinus Pain Relief, Runny Nose, Congestion, Sinus Pressure, Headache - 60 Count
Main highlights

Homeopathic Sinus Relief
Targets sinus pain with a stuffy or runny nose, non-drowsy, and non-habit forming.

Convenient for All Ages
Sweet pellets melt under the tongue, suitable for ages 6 and up.

Effective Symptom Relief
Praised for effectively stopping constant runny nose and congestion.
8.6

Very Good

Our Rating

9.3
simple to consume

8.2
Flavor

8.0
worth the money
8

ALKA-SELTZER PLUS
Alka-Seltzer Plus Maximum Strength Power Max Sinus, Allergy and Cough Medicine for Adults and Children 12 Years and Older - Relieves Symptoms from Allergies, Colds or Hay Fever, 24 Count
Main highlights

Powerful Allergy and Sinus Relief
Alka-Seltzer Plus Maximum Strength Powermax gels provide effective relief from allergies and sinus issues.

Ideal for Cold and Allergy Symptoms
Use for colds, hay fever, and allergy symptom relief.

Quick and Effective Relief
Customers praise its quick action and effectiveness in relieving symptoms.
Key specs
- dosage:Maximum Strength
- form:Gels
- symptom relief:Allergy and sinus
- active ingredient:N/A
- flavor:N/A
8.4

Good

Our Rating

9.3
worth the money

9.3
Flavor

9.1
simple to consume
9

NUVICARE
NUVICARE Max Strength PE Phenylephrine HCl 10mg Non Drowsy Nasal Decongestant - Allergy Sinus Congestion Relief Compare to Sudafed PE Decongestant Tablets - Sinus Decongestants for Adults (100 Count)

23% Off
Main highlights

Powerful Nasal Decongestion
Contains phenylephrine HCl 10mg for direct nasal congestion relief.

Ideal for Daytime Use
Non-drowsy formula allows for all-day relief without drowsiness.

Highly Recommended by Users
Praised for effectiveness and ease of use compared to brands.
Key specs
- dosage:10 mg
- form:Tablet
- symptom relief:Nasal congestion
- active ingredient:Phenylephrine HCl 10mg
- flavor:N/A
8.3

Good

Our Rating
10

Vicks
Vicks Sinex SEVERE LiquiCaps, All-In-One Sinus Relief, Non-Drowsy, Nasal Decongestant, Maximum Strength Relief of Sinus Headache, Pain, Pressure, & Congestion, 24 LiquiCaps
Main highlights

Fast Relief from Nasal Congestion
Experience fast, powerful relief from nasal congestion and sinus pain.

Ideal for Sinus Symptoms from Allergies
Best for treating sinus symptoms caused by colds and allergies.

Highly Effective for Sinus Headaches
Commonly praised for quickly alleviating sinus pressure headaches.
Key specs
- features:Fast relief from congestion
- product dimensions:4.4 x 1.1 x 3.3 inches
- decongestant:Nasal decongestant
- active ingredients:N/A
- usage instructions:N/A
8.2

Good

Our Rating

9.3
simple to consume

9.3
worth the money

8.9
pain management

Sinus Medicines of 2025

1

Mucinex Sinus-Max Day Pressure, Pain & Cough & Nightshift Night Sinus Medicine for Adults, Day/Night Combo Pack for Sore Throat Relief, Nasal Congestion Relief, Cough & Cold Medicines, 40 Caplets

9.3

8.9

How do we rank?

How do we rank?

Analyzing top stores

2

Advil Sinus Congestion and Pain, Sinus Relief Medicine, Pain Reliever and Fever Reducer with Ibuprofen and Phenylephrine HCl - 20 Coated Tablets

9.7

9.3

8.0

3

Mucinex Sinus-Max Severe Congestion Relief Caplets, 20 Count

4

GenCare - Nasal Decongestant (10mg Tablets) Phenylephrine HCl (300 Tablets Per Bottle) | Value Pack Non Drowsy Sinus and Nasal Congestion Relief | Lower Sinus Pressure Due to Allergies or Illness

9.7

9.5

9.3

5

Sudafed PE Head Congestion + Mucus Tablets for Sinus Pressure, Pain & Congestion, 24 ct

9.9

9.7

8.0

6

Vicks Sinex SEVERE Allergy & Sinus Nasal Spray, Original Ultra Fine Mist, Decongestant Medicine, Relief from Nasal Congestion due to Cold or Allergy, Sinus Pressure Relief, 265 Sprays x 2

9.5

9.3

9.1

7

Boiron SinusCalm Tablets for Sinus Pain Relief, Runny Nose, Congestion, Sinus Pressure, Headache - 60 Count

9.3

8.2

8.0

8

Alka-Seltzer Plus Maximum Strength Power Max Sinus, Allergy and Cough Medicine for Adults and Children 12 Years and Older - Relieves Symptoms from Allergies, Colds or Hay Fever, 24 Count

9.3

9.3

9.1

9

NUVICARE Max Strength PE Phenylephrine HCl 10mg Non Drowsy Nasal Decongestant - Allergy Sinus Congestion Relief Compare to Sudafed PE Decongestant Tablets - Sinus Decongestants for Adults (100 Count)

10

Vicks Sinex SEVERE LiquiCaps, All-In-One Sinus Relief, Non-Drowsy, Nasal Decongestant, Maximum Strength Relief of Sinus Headache, Pain, Pressure, & Congestion, 24 LiquiCaps

9.3

9.3

8.9

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Advil Sinus Congestion and Pain, Sinus Relief Medicine, Pain Reliever and Fever Reducer with Ibuprofen and Phenylephrine HCl - 10 Coated Tablets

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Sudafed PE Sinus Congestion Day + Night Maximum Strength Decongestant & Antihistamine Tablets with Phenylephrine HCl & Diphenhydramine HCl, Helps Nasal & Sinus Pressure & Congestion, 20 ct

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HealthA2Z® Decongestant PE | Phenylephrine HCl 10 mg | Maximum Strength | Nasal & Sinus Congestion Relief Due to Cold & Allergies (300 Count (Pack of 1))

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Benadryl Allergy Plus Congestion Ultratabs, Medicine with Diphenhydramine HCl Antihistamine & Phenylephrine HCl Nasal Decongestant, Allergy & Sinus Congestion Relief Tablets, 24 ct

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Boiron SinusCalm Allergy Tablets for Relief from Sinus Pressure, Sinus Headache, or Sinus Congestion and Pain - 60 Count

$10.39

Advil Sinus Congestion and Pain, Sinus Relief Medicine, Pain Reliever and Fever Reducer with Ibuprofen and Phenylephrine HCl - 50 Coated Tablets

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