Sinus Medicines of 2025
Best Choice1
Mucinex15% OffMucinex Sinus-Max Day Pressure, Pain & Cough & Nightshift Night Sinus Medicine for Adults, Day/Night Combo Pack for Sore Throat Relief, Nasal Congestion Relief, Cough & Cold Medicines, 40 Caplets
9.3 simple to consume8.9 worth the moneyWhy we love it
Fast-acting relief for multiple symptoms.
Trusted by doctors for cold and cough.
Effective during severe allergy seasons.
9.6Exceptional
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Value for Money2
GenCare16% OffGenCare - Nasal Decongestant (10mg Tablets) Phenylephrine HCl (300 Tablets Per Bottle) | Value Pack Non Drowsy Sinus and Nasal Congestion Relief | Lower Sinus Pressure Due to Allergies or Illness
9.7 worth the money9.5 dispense easily9.3 simple to consumeWhy we love it
Effective non-drowsy decongestant.
Convenient bulk savings bottle.
Easy to find online.
9.4Excellent
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3
Sudafed15% OffSudafed PE Sinus Pressure + Pain Relief Tablets, Maximum Strength, Non-Drowsy, OTC Sinus Relief Medicine with Acetaminophen Pain Reliever & Phenylephrine HCl Nasal Decongestant, 24 ct
9.1 simple to consume8.4 worth the money8.0 ComfortWhy we love it
Non-drowsy formula for daytime use.
Effective against sinus pressure and pain.
Trusted brand with positive customer feedback.
9.3Excellent
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4
Mucinex21% OffMucinex Sinus-Max Severe Congestion Relief Caplets, 20 Count
Why we love it
Effective relief for multiple congestion types.
Trusted brand by doctors.
Compact packaging for easy use.
9.1Excellent
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5
AdvilAdvil Sinus Congestion and Pain, Sinus Relief Medicine, Pain Reliever and Fever Reducer with Ibuprofen and Phenylephrine HCl - 20 Coated Tablets
9.7 pain management9.3 simple to consume8.0 Packaging materialsWhy we love it
Effective for sinus and headache relief.
Convenient single-tablet dosing.
Portable for easy, anytime relief.
8.9Very Good
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6
SudafedSudafed PE Sinus Congestion Day + Night Maximum Strength Decongestant & Antihistamine Tablets with Phenylephrine HCl & Diphenhydramine HCl, Helps Nasal & Sinus Pressure & Congestion, 20 ct
9.5 simple to consume8.7 worth the money8.4 pain managementWhy we love it
Effective day and night relief.
Includes antihistamine for nighttime symptoms.
Highly recommended by users.
8.8Very Good
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7
Sudafed15% OffSudafed PE Head Congestion + Mucus Tablets for Sinus Pressure, Pain & Congestion, 24 ct
9.9 simple to consume9.7 pain management8.0 For Gentle skinWhy we love it
Non-drowsy formula ensures daytime use.
Effective for sinus and chest congestion.
Highly recommended for stuffy nose relief.
8.7Very Good
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8
BoironBoiron SinusCalm Tablets for Sinus Pain Relief, Runny Nose, Congestion, Sinus Pressure, Headache - 60 Count
9.3 simple to consume8.2 Flavor8.0 worth the moneyWhy we love it
Non-drowsy formula.
Easy to use for all ages.
Effective for runny nose.
8.6Very Good
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9
VicksVicks Sinex SEVERE LiquiCaps, All-In-One Sinus Relief, Non-Drowsy, Nasal Decongestant, Maximum Strength Relief of Sinus Headache, Pain, Pressure, & Congestion, 24 LiquiCaps
9.3 simple to consume9.3 worth the money8.9 pain managementWhy we love it
Fast relief from sinus symptoms.
Non-drowsy formula.
Effective for sinus headaches.
8.5Good
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10
Vicks14% OffVicks Sinex SEVERE Allergy & Sinus Nasal Spray, Original Ultra Fine Mist, Decongestant Medicine, Relief from Nasal Congestion due to Cold or Allergy, Sinus Pressure Relief, 265 Sprays x 2
9.5 Simple to use9.3 Moisturizing9.1 worth the moneyWhy we love it
Long-lasting 12-hour relief.
Direct application to nasal membranes.
Highly effective for severe congestion.
8.3Good
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