Our rankings are cleverly generated from the algorithmic analysis of thousands of customer reviews about products, brands, merchant’s customer service levels, popularity trends, and more. The rankings reflect our opinion and should be a good starting point for shopping. By purchasing the products we rank, you’ll get the lowest price we found while we may receive a commission at no cost to you, which will help us continue to provide you with value.
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Gamer Mouse Ergonomics of 2025
Save up to 42% off
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- Value for Money
2
RazerRazer Basilisk V3 Customizable Ergonomic Gaming Mouse: Fastest Gaming Mouse Switch - Chroma RGB Lighting - 26K DPI Optical Sensor - 11 Programmable Buttons - HyperScroll Tilt Wheel - Classic Black
42% OffMain highlights-
Ergonomic Design with Thumb Rest
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Versatile Gaming and Office Use
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Praised Hyperscroll Tilt Wheel
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3
TRELCTRELC Gaming Mouse with 5 D Rocker, Ergonomic Mouse with 10000 DPI/11 Programmable Buttons, Vertical Gaming Mice Wired for PC/Laptop/E-Sports/Gamer (Black)
Main highlights-
Ergonomic Design Benefits
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Ideal for Gaming Enthusiasts
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Praised Comfort and Wrist Relief
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4
RedragonRedragon M908 Impact RGB LED MMO Gaming Mouse with 12 Side Buttons, Optical Wired Ergonomic Mouse with Max 12,400DPI, High Precision, 18 Programmable Macro Shortcuts, Comfort Grip
30% OffMain highlights-
High Precision and Customization
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Ideal for MMO Gaming
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Highly Praised Comfort
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5
ZeerkeerZeerkeer Ergonomic Vertical Mouse, RGB Wired Vertical Gaming Mouse with Joystick, 10000 Max DPI and 11 Programmable Buttons for Gamers, Computer (Wired)
Main highlights-
Ergonomic and Programmable Features
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Ideal Use Cases
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Customer Reviews Highlight
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See Today’s Deals & Prices
6
J-Tech DigitalJ-Tech Digital Wired Ergonomic Vertical USB Mouse with Adjustable Sensitivity (600/1000/1600 DPI), Scroll Endurance, Removable Palm Rest & Thumb Buttons [V628]
20% OffMain highlights-
Ergonomic Design
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Ideal Use Cases
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Customer Reviews
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7
RedragonRedragon Gaming Mouse, Wireless Mouse Gaming with 8000 DPI, PC Gaming Mice with Fire Button, RGB Backlit Programmable Ergonomic Mouse Gamer, Rechargeable, 70Hrs for Windows, Mac Gamer, Black
25% OffMain highlights-
Wireless Programmable Gaming Mouse
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Ideal for Gaming and Productivity
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Highly Praised Ergonomic Design
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8
ProtoArcProtoArc Ergonomic Mouse, EM11 NL Bluetooth Rechargeable Wireless Vertical Mouse, 3 Multi-Device Connectivity for Computer/PC/Laptop, 2.4GHz Optical Mice for Windows, Mac OS, Black
Main highlights-
Ergonomic Design Benefit
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Multi-Device Usability
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Customer Praised Comfort
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9
ZLOTZLOT Vertical Gaming Mouse,Wired RGB Ergonomic USB Joystick Programmable Laser Gaming Mice,6+1 Design,11 Buttons,1000 Hz Max Polling Rate,10000 Max DPI,Upgraded Version for Computer Gamers,Black
Main highlights-
Key Features
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Ideal Use Cases
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Customer Reviews Highlight
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10
AnkerAnker 2.4G Wireless Vertical Ergonomic Optical Mouse for Work, Multi-Device Connectivity, 800/1200 /1600 DPI, 5 Buttons for Laptop, Desktop, PC, MacBook - Black
Main highlights-
Ergonomic Design for Comfort
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Ideal for Office and Home Use
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Praised for Wrist Pain Relief
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Redragon M602 Gaming Mouse, Ergonomic RGB Gaming Mouse Wired with 7200 Adjustable DPI, 9 Programmable Buttons, Professional Software for Gamer Office [Black]
【Classics Last Longer】Redragon Gaming Mouse - M602 was launched in 2015, It is Professional and Durable with a positive rating of 96.8%, a quality product with historical verification.$19.99
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MEETION Ergonomic Mouse, Wireless Vertical Mouse RGB Backlit Rechargeable Mice for Bluetooth(5.2 + 3.0) & USB-A with USB-C Adapter 4 Adjustable DPI for Mac/Windows/Andriod/PC/Tablet/iPad Black
【ERGONOMIC VERTICAL MOUSE】 BTM010 ergonomic vertical mouse is meticulously crafted with a unique vertical shape that reduces wrist and forearm strain, delivering a comfortable and natural grip. It promotes a more ergonomic posture, alleviating discomfort and enhancing overall comfort.$19.98
- 20% OffFree Shipping
Honeycomb Wired Gaming Mouse with RGB On/Off Switch, 7200 Adjustable DPI, Ergonomic Lightweight Design & High Precision Sensor for PC/Mac Gamers (Black)
【16.8 Million Color RGB Lighting】★The new inventory allows you to toggle the RGB lighting—simply press the side button and middle button together for 3 seconds to switch it on or off. Immerse yourself in the game with dynamic RGB lighting that cycles through 16.8 million colors. Set the mood for victory and dominate in style.$9.99
$12.50 (20% Off) - 20% OffFree Shipping
shoplease Wired Vertical Mouse, Optical Ergonomic Mouse with 4 Adjustable 800/1200/2000/3200, 5 Buttons USB Computer Mouse, Better for Large and Medium Sized Hands
【Ergonomic Design】-Scientific ergonomic design encourages healthy neutral "handshake" wrist and arm positions for smoother movement and less overall strain. (Note: it is a right-handed mouse)$9.49
$11.99 (20% Off) - Free Shipping
SOLAKAKA RGB Wired Gaming Mouse with Honeycomb Shell,Adjustable 12800 DPI,7 Programmable Buttons,Lightweight Gaming Mice Ergonomic Computer Mouse Gaming for Windows/PC/Mac/Laptop Gamer
6 Levels Adjustable DPI:SM900 is a powerful gaming mouse with excellent performance,It supports 6 levels adjustment DPI up to 12800.Rolling Rate max to 1000Hz,According user's preference setup different DPI and Rolling Rate suitable for games, office and many occasions$19.89
- 25% OffFree Shipping
MOJO Silent Vertical Gaming Mouse - Ergonomic Mouse for PC Gaming w/ 4 Directional Joystick Buttons, Adjustable DPI (1000-10000), Custom Software, Macros, and More
Combines a top quality gaming sensor with a comfortable ergonomically designed vertical mouse so you can play and work all day.$29.99
$39.99 (25% Off) - 10% OffFree Shipping
TECKNET Ergonomic Mouse, Wireless Bluetooth Vertical Mouse, 4800 DPI Optical Tracking, 6 Adjustable DPI, Quiet Clicks, 2.4GHz with USB A Receiver, 6 Buttons, Wide Compatibility - Black
【Seamless Switching Between Three Devices】The ergonomic mouse features Bluetooth (5.0/3.0) and 2.4GHz USB A modes for connectivity. When connected via Bluetooth, The vertical mouse can effectively reduces the usage of your USB-A port (Bluetooth mode can connect to two devices simultaneously), which is convenient for devices without USB ports. To switch to 2.4GHz mode, simply plug in the USB receiver for quick connection without the need for additional software installation. With just a press of a button, you can easily switch between these two modes, enhancing your work efficiency (Note: The 2.4GHz receiver is built into the bottom of the mouse).$26.99
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memzuoix Ergonomic Mouse Wireless,2.4G Optical Cordless Mice with 800/1200/1600 DPI,Vertical Computer Wireless Mouse for Laptop, Mac,PC,Desktop (for Right Hand, Large),Blue Mouse
Ergonomic Mouse for Your Right Hand: The wireless mouse with upgraded optical ergonomic and friendly design keeps your hand and arm staying more naturally. The ergonomic shape encourages healthy neutral "handshake" wrist and arm positions. Effectively smoother movement and less overall strain,compared with a regular wireless mouse.(The forward/back buttons are not compatible with Mac OS)$24.99
- Free Shipping
Redragon M690 PRO Wireless Gaming Mouse, 8000 DPI Wired/Wireless Gamer Mouse w/Rapid Fire Key, 8 Macro Buttons, Ergonomic Design for PC/Mac/Laptop
Wireless for Boundless Winning – The 2.4Ghz wireless enables working distances up to 10 meters (or approx. 30ft) with a little-to-no delay or signal drops. Giving the best play gaming experience and taking your shot with precise timing to victory.$24.99
- 30% OffFree Shipping
Redragon Wireless Gaming Mouse, Ergonomic Mouse 16000 DPI with Rapid Fire Key, 9 Macro Buttons, 170-Hour Durable Power Capacity and RGB Backlight Wired/Wireless Mouse for Laptop/Mac/PC
WIRELESS FOR BOUNDLESS WINNING: Redragon wireless gaming mouse with 2.4Ghz nano receiver offers you the purest mouse moving experience and hype your KDA rise again. The rechargeable wireless mouse has a battery life between 13 hours (RGB on) and 170 hours (RGB off) on a single charge$31.99
$45.99 (30% Off)