Our rankings are cleverly generated from the algorithmic analysis of thousands of customer reviews about products, brands, merchant’s customer service levels, popularity trends, and more. The rankings reflect our opinion and should be a good starting point for shopping. By purchasing the products we rank, you’ll get the lowest price we found while we may receive a commission at no cost to you, which will help us continue to provide you with value.
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Ergonomic Vertical Wireless Mice of 2025
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1
LogitechLogitech MX Vertical Wireless Mouse – Ergonomic Design Reduces Muscle Strain, Move Content Between 3 Windows and Apple Computers, Rechargeable, Graphite
16% OffMain highlights-
Ergonomic Design Benefit
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Ideal for Multi-Device Use
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Praised for Comfort
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2
LogitechLogitech Lift Vertical Ergonomic Mouse, Wireless Bluetooth or USB Receiver, Quiet Clicks, 4 Buttons, Right Hand Wireless Mouse, Windows/macOS/iPadOS, Laptop, PC - Graphite
Main highlights-
Ergonomic Comfort
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Versatile Connectivity
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Quiet Clicks
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3
AnkerAnker 2.4G Wireless Vertical Ergonomic Optical Mouse for Work, Multi-Device Connectivity, 800/1200 /1600 DPI, 5 Buttons for Laptop, Desktop, PC, MacBook - Black
Main highlights-
Ergonomic Design for Comfort
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Ideal for Office and Home Use
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Praised for Wrist Pain Relief
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4
ProtoArcProtoArc Ergonomic Mouse, EM11 NL Bluetooth Rechargeable Wireless Vertical Mouse, 3 Multi-Device Connectivity for Computer/PC/Laptop, 2.4GHz Optical Mice for Windows, Mac OS, Black
Main highlights-
Ergonomic Design Benefit
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Multi-Device Usability
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Customer Praised Comfort
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5
TECKNETTECKNET Ergonomic Mouse, Wireless Bluetooth Vertical Mouse, 4800 DPI Optical Tracking, 6 Adjustable DPI, Quiet Clicks, 2.4GHz with USB A Receiver, 6 Buttons, Wide Compatibility - Black
10% OffMain highlights-
Seamless Device Connectivity
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Ideal for Office Use
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Ergonomic Comfort
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TECKNETTECKNET Ergonomic Mouse Wireless, Rechargeable Mouse Wireless Silent for Carpal Tunnel Right Hand, 2.4GHz USB Vertical Mouse Wireless for Laptop, 5 Adjustable 4800 DPI, Computer, MacBook, Desktop
Main highlights-
Ergonomic Design
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Ideal for Quiet Spaces
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Rechargeable Battery Life
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TECKNETTECKNET Ergonomic Mouse, Rechargeable 2.4G+Bluetooth Vertical Mice 6 DPI Adjustable, Wireless Optical Carpal Tunnel Mouse for Right Hand, Silent 6 Buttons for Laptop, PC, MacBook, iPad - Black
Main highlights-
Simultaneous Device Connection
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Ergonomic Comfort for Arm Protection
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Customer Favorite Feature - Ergonomic Design
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9
POJTKPOJTK Ergonomic Wireless Rechargeable Mouse, Bluetooth+USB A+Type C(3 in 1) Connection, 5 Levels Up to 4800 DPI, 6 Silent Buttons, 2.4GHz Carpal Tunnel Vertical Mice, for Laptop, Desktop,MacBook-black
Main highlights-
Ergonomic Design and Comfort
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Versatile Connectivity Options
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Silent Operation
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10
KensingtonKensington Ergonomic Vertical Wireless Mouse (K75575WW), Grey/Black
Main highlights-
Key Features
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Ideal Use Cases
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Customer Praise
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- 55% OffFree Shipping
Lekvey Ergonomic Mouse, Vertical Wireless Mouse - Rechargeable 2.4GHz Optical Vertical Mice : 3 Adjustable DPI 800/1200/1600 Levels 6 Buttons, for Laptop, PC, Computer, Desktop, Notebook etc, Black
Ergonomic, Sleek and Rechargeable Design: Scientific ergonomic design encourages healthy neutral " handshake " wrist and arm positions for smoother movement and less overall strain$17.98
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JYKEYMOUT Bluetooth and 2.4G (2-in-1) Rechargeable Wireless Mouse, Ergonomic Vertical Design, 1000/1200/1600 DPI, 6 Silent Buttons, for Laptop, Computer, PC, MacBook, Chromebook-Black
【2-in-1 (Bluetooth & 2.4G) Dual Mode】The wireless PC mouse features both Bluetooth (5.2/3.0) and 2.4GHz USB modes. Opt for Bluetooth mode to connect to a laptop or tablet, saving a USB-A port. Especially convenient for MacBook Pro without USB port. Or choose the 2.4GHz USB mode, simply plug in the USB receiver for quick connection without the pairing process. Effortlessly switch between the two modes with the press of a button for flexible use according to your needs.$9.99
- 20% OffFree Shipping
Lekvey Ergonomic Mouse, Vertical Wireless Mouse, Rechargeable 2.4G Optical Carpal Tunnel Mice: 800/1200 / 1600 DPI, 6 Buttons, for Laptop, PC, Computer, Desktop, Notebook etc, Green Purple
Ergonomic, Sleek, and Trendy Colors Design: Scientific ergonomic design encourages healthy neutral "handshake" wrist and arm positions for smoother movement and less overall strain. This could be your choice if you want an ergonomic, colorful mouse; Also, the various color options and the vertical design make it the ultimate choice for home, office, libraries, dormitories, high-speed rail, airplanes, or traveling use$19.99
$24.99 (20% Off) - 57% OffFree Shipping
Lekvey Ergonomic Mouse, Vertical Wireless Mouse: Rechargeable Optical Carpal Tunnel Mice with 2.4G USB Receiver, 1000/1200 / 1600 DPI, 6 Buttons, for Laptop, Computer, PC, Desktop, Notebook, Black
Ergonomic Mouse, Vertical Sleek Design: Experience natural fatigue relief and pain-free comfort. This cool wireless ergonomic mouse encourages a healthy, natural handshake grip, providing support for your forearm and wrist to minimize carpal tunnel strain and discomfort compared to standard mice. It is ideal for office workers, designers, travelers, and anyone in search of an all-day comfortable mouse. Relax your palm and enjoy a seamless, pain-free workflow$16.99
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TECKNET Ergonomic Mouse, 4800 DPI Wireless Vertical Mouse, 5 Adjustable DPI Levels, 6 Buttons, 2.4G Silent Wireless Mouse for Laptop, PC, Chromebook, Mac - Black
【Ergonomic Design】Ergonomic mouse with Ergonomic Design, 52°angle to the tabletop. A natural handshake position effectively relieves pressure on the wrist and arm, preventing RSI syndrome caused by long-term mouse use. It is the ideal choice for prolonged office work$17.99
- 25% OffFree Shipping
Ergodriven Om Handshake Vertical Mouse | Wireless Ergonomic Mouse | Rechargeable | Silent Click Micro-Force Switches | OLED Screen | Reduces Tension and Fatigue | Compatible with PC and Mac
PERFECT ERGONOMICS. You hold your mouse for hours every day, so it's critical to use a good one! A vertical mouse is a must, and Om has the most ergonomic shape on the market, plus silent, micro-force buttons to further reduce tension and fatigue.$29.00
$39.00 (25% Off) - Free Shipping
MEETION Ergonomic Mouse, Wireless Vertical Mouse RGB Backlit Rechargeable Mice for Bluetooth(5.2 + 3.0) & USB-A with USB-C Adapter 4 Adjustable DPI for Mac/Windows/Andriod/PC/Tablet/iPad Black
【ERGONOMIC VERTICAL MOUSE】 BTM010 ergonomic vertical mouse is meticulously crafted with a unique vertical shape that reduces wrist and forearm strain, delivering a comfortable and natural grip. It promotes a more ergonomic posture, alleviating discomfort and enhancing overall comfort.$19.98
- 64% OffFree Shipping
memzuoix Ergonomic Mouse Wireless,2.4G Optical Cordless Mice with 800/1200/1600 DPI,Vertical Computer Wireless Mouse for Laptop, Mac,PC,Desktop (for Right Hand, Large),Blue Mouse
Ergonomic Mouse for Your Right Hand: The wireless mouse with upgraded optical ergonomic and friendly design keeps your hand and arm staying more naturally. The ergonomic shape encourages healthy neutral "handshake" wrist and arm positions. Effectively smoother movement and less overall strain,compared with a regular wireless mouse.(The forward/back buttons are not compatible with Mac OS)$8.99
$24.99 (64% Off) - Free Shipping
ECHTPower Ergonomic Wireless Mouse, Bluetooth Vertical Mouse with LED Light, Control Up to 3 Devices (BT5.0+BT5.0+2.4GHz), Adjustable DPI 2400/1600/1000, for PC, Laptop, Mac, Windows
【Ergonomic Vertical Design】Crafted with a right-handed ergonomic vertical shape that naturally aligns with the curvature of your palm, reducing wrist strain and promoting a healthier posture during prolonged use.$22.99
- 18% OffFree Shipping
Uineer Vertical Mouse Wireless,Bluetooth Mouse with BT5.0/4.0/2.4G, Rechargeable with Battery Indicator,Ergonomic Design for Comfort and Reduced Wrist Strain, Ideal for Home,Office Use,Black
Ergonomic Design for Comfort: The vertical mouse provides an ergonomic mouse solution with a comfortable grip, reducing wrist strain and promoting better posture for long-term use. Ideal for ergonomic mouse wireless needs. Mouse Dimensions: L x W x H 11.6 x 7.2 x 7.5 cm /4.57 x 3.03 x 2.95 inches.$21.98
$26.99 (18% Off)