Our rankings are cleverly generated from the algorithmic analysis of thousands of customer reviews about products, brands, merchant’s customer service levels, popularity trends, and more. The rankings reflect our opinion and should be a good starting point for shopping. By purchasing the products we rank, you’ll get the lowest price we found while we may receive a commission at no cost to you, which will help us continue to provide you with value.
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Ergonomic Mause Wirelesses of 2025
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- Best Choice
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LogitechLogitech MX Vertical Wireless Mouse – Ergonomic Design Reduces Muscle Strain, Move Content Between 3 Windows and Apple Computers, Rechargeable, Graphite
16% OffMain highlights-
Ergonomic Design Benefit
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Ideal for Multi-Device Use
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Praised for Comfort
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3
TECKNETTECKNET Wireless Mouse, 2.4G Ergonomic Optical Mouse, Computer Mouse for Laptop, PC, Computer, Chromebook, Notebook, 6 Buttons, 24 Months Battery Life, 2600 DPI, 5 Adjustment Levels
37% OffMain highlights-
Compact Travel Friendly Design
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Ideal for Everyday Use
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Ergonomic Comfort
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TECKNETTECKNET Ergonomic Mouse, Wireless Bluetooth Vertical Mouse, 4800 DPI Optical Tracking, 6 Adjustable DPI, Quiet Clicks, 2.4GHz with USB A Receiver, 6 Buttons, Wide Compatibility - Black
10% OffMain highlights-
Seamless Device Connectivity
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Ideal for Office Use
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Ergonomic Comfort
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AnkerAnker 2.4G Wireless Vertical Ergonomic Optical Mouse, 800 / 1200 /1600DPI, 5 Buttons - Black
Main highlights-
Ergonomic Design for Comfort
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Ideal for Office and Home Use
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Praised for Wrist Pain Relief
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ProtoArcProtoArc Ergonomic Mouse, EM11 NL Bluetooth Rechargeable Wireless Vertical Mouse, 3 Multi-Device Connectivity for Computer/PC/Laptop, 2.4GHz Optical Mice for Windows, Mac OS, Black
Main highlights-
Ergonomic Design Benefit
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Multi-Device Usability
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Customer Praised Comfort
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LogitechLogitech Lift Vertical Ergonomic Mouse, Wireless, Bluetooth or Logi Bolt USB receiver, Quiet clicks, 4 buttons, compatible with Windows/macOS/iPadOS, Laptop, PC - Off White
Main highlights-
Ergonomic Design Benefits
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Ideal for Office Use
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Praised for Comfort
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MEETIONMEETION Ergonomic Wireless Keyboard and Mouse, Ergo Keyboard with Vertical Mouse, Split Cushioned Wrist Palm Rest, Natural Typing, Rechargeable, Full Size, Windows/Mac/Computer/Laptop, Black DirectorC
10% OffMain highlights-
Split Keyboard Ergonomics
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Ideal for Extended Use
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Praised Wrist Support
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10
AnkerAnker Ergonomic Optical USB Wired Vertical Mouse 1000/1600 DPI, 5 Buttons CE100
Main highlights-
Ergonomic Design for Comfort
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Ideal for Office and Gaming
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Highly Praised for Pain Relief
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Similar products on Amazon
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TECKNET Ergonomic Mouse Wireless, Rechargeable Mouse Wireless Silent for Carpal Tunnel Right Hand, 2.4GHz USB Vertical Mouse Wireless for Laptop, 5 Adjustable 4800 DPI, Computer, MacBook, Desktop
Ergonomic Design: This ergonomic mouse promotes a natural wrist and arm position, minimizing hand fatigue from prolonged use. With a vertical layout, the vertical mouse aids in maintaining a comfortable posture, reducing shoulder and neck strain.$23.99
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POJTK Ergonomic Wireless Rechargeable Mouse, Bluetooth+USB A+Type C(3 in 1) Connection, 5 Levels Up to 4800 DPI, 6 Silent Buttons, 2.4GHz Carpal Tunnel Vertical Mice, for Laptop, Desktop,MacBook-black
【Vertical ergonomic design】POJTK ergonomic mouse adopts a scientific vertical design, with an angle of 58 degrees to the desktop. It fits the curvature of the palm very well, encourages a healthy and neutral "handshake" posture, and provides ultimate comfort. Promote smoother movement, reduce stress on the wrist and arm, and relieve wrist muscle fatigue and pain.$22.99
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Amazon Basics Computer Mouse Wireless, Ergonomic, 2.4 GHz Optical, DPI Adjustable, Compatible With PC, Mac, Laptop, Black
COMFORTABLE NAVIGATION: The wireless mouse is designed for smooth and easy computer interface navigation, and provides ease of use for prolonged periods without strain$10.45
$11.58 - 20% OffFree Shipping
Lekvey Ergonomic Mouse, Vertical Wireless Mouse Rechargeable 2.4 GHz Optical Carpal Tunnel Mouse : 800/1200 / 1600 DPI, 6 Buttons, for Laptop, PC, Computer, Desktop, Notebook etc, Pink to Purple
Ergonomic, Sleek, and Trendy Colors Design: Scientific ergonomic design encourages healthy neutral "handshake" wrist and arm positions for smoother movement and less overall strain. This could be your choice if you want an ergonomic, colorful mouse; Also, the various color options and the vertical design make it the ultimate choice for home, office, libraries, dormitories, high-speed rail, airplanes, or traveling use$19.99
$24.99 (20% Off) - Free Shipping
cimetech Wireless Mouse Bluetooth, 1 Mice for 2 Devices, Rechargeable Comfort Silent Ratones for PC Laptop Computer, Portable Ergonomic Mäuse with Nano Receiver and Cable for School and Home Office
【Wide Compatibility】 Bluetooth mode: Compatible with more than 99.9% Bluetooth devices. 2.4GHz USB mode: Simply plug the USB-A mini-receiver into your computer. Compatibility with Windows, macOS, Linux, ChromeOS, iPadOS, and Android operating systems; Connect Pad, Phone, Macbook Pro Air, Laptop, Notebook, PC, Computer and so on.$18.99
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Usbkingdom 2.4GHz Wireless Mouse Cool 3D Sport Car Shape Ergonomic Optical Mice Mause with USB Receiver for PC Laptop Computer Women Small Hands (Black)
Wireless mouse sports car shape with 7 color breathing LED headlight, cool gaming mouse for laptop computer, good choice for using or as gifts for family, friends, women, and men$16.12
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TECKNET Vertical Wireless Mouse, Ergonomic Mouse for Small Hands, 4800DPI, 5 Adjustable DPI Levels, 6 Buttons, 2.4GHz Silent Optical Wireless Mouse for Laptop, Computers, PCs, Macs - Black
Enjoy Comfort: With a 57° vertical design that matches the natural handshake posture, the TECKNET ergonomic mouse allows your hand to easily lift and nestle on the comfortable thumb rest, reducing wrist pressure and providing a comfortable and fatigue-free grip and use experience$19.99
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JYKEYMOUT Bluetooth and 2.4G (2-in-1) Rechargeable Wireless Mouse, Ergonomic Vertical Design, 1000/1200/1600 DPI, 6 Silent Buttons, for Laptop, Computer, PC, MacBook, Chromebook-Black
【2-in-1 (Bluetooth & 2.4G) Dual Mode】The wireless PC mouse features both Bluetooth (5.2/3.0) and 2.4GHz USB modes. Opt for Bluetooth mode to connect to a laptop or tablet, saving a USB-A port. Especially convenient for MacBook Pro without USB port. Or choose the 2.4GHz USB mode, simply plug in the USB receiver for quick connection without the pairing process. Effortlessly switch between the two modes with the press of a button for flexible use according to your needs.$9.99
- 57% OffFree Shipping
Lekvey Ergonomic Mouse, Vertical Wireless Mouse: Rechargeable Optical Carpal Tunnel Mice with 2.4G USB Receiver, 1000/1200 / 1600 DPI, 6 Buttons, for Laptop, Computer, PC, Desktop, Notebook, Black
Ergonomic Mouse, Vertical Sleek Design: Experience natural fatigue relief and pain-free comfort. This cool wireless ergonomic mouse encourages a healthy, natural handshake grip, providing support for your forearm and wrist to minimize carpal tunnel strain and discomfort compared to standard mice. It is ideal for office workers, designers, travelers, and anyone in search of an all-day comfortable mouse. Relax your palm and enjoy a seamless, pain-free workflow$16.99
$39.99 (57% Off) - 55% OffFree Shipping
Lekvey Ergonomic Mouse, Vertical Wireless Mouse - Rechargeable 2.4GHz Optical Vertical Mice : 3 Adjustable DPI 800/1200/1600 Levels 6 Buttons, for Laptop, PC, Computer, Desktop, Notebook etc, Black
Ergonomic, Sleek and Rechargeable Design: Scientific ergonomic design encourages healthy neutral " handshake " wrist and arm positions for smoother movement and less overall strain$17.98
$39.99 (55% Off)