Cold And Flus of 2025

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Last Updated - May 13, 2025

Best Choice

1

Clicked 37 times in the last month

Vicks
Vicks DayQuil & NyQuil Ultra Concentrated Liquicaps Co-Pack, Cold & Flu Medicine, Powerful Multi-Symptom Daytime & Nighttime Relief for Headache, Fever, Sore Throat, Minor Aches & Pains, & Cough, 96ct
Main highlights

WORLD'S #1 SELLING OTC COUGH AND COLD BRAND. Vicks has been trusted for over 125 years to relieve your worst cold & flu symptoms.
STOCK UP: Make sure your family has the medicine you need, when you need it!
POWERFUL, FAST-ACTING, MULTI-SYMPTOM RELIEF: DayQuil & NyQuil Ultra Concentrated Cold & Flu medicine temporarily relieves your worst cold & flu symptoms
EASY TO OPEN BOTTLE: No more scissors or knives necessary! Liquicaps now in an easy to open twist top bottle
25% SMALLER LIQUICAPS: Ultra Concentrated Liquicaps designed to be 25% smaller than original DayQuil/NyQuil Liquicaps
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9.8

Exceptional

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Our rankings are cleverly generated from the algorithmic analysis of thousands of customer reviews about products, brands, merchant’s customer service levels, popularity trends, and more. The rankings reflect our opinion and should be a good starting point for shopping. By purchasing the products we rank, you’ll get the lowest price we found while we may receive a commission at no cost to you, which will help us continue to provide you with value.
Value for Money

2

Boiron
Boiron Oscillococcinum For Relief From Flu-Like Symptoms Of Body Aches, Headache, Fever, Chills, And Fatigue - 30 Count

24% Off

9.7 simple to consume

9.7 Simple to use

9.7 Flavor

Why we love it

Safe for all family members.

Quick and easy to take.

Reduces flu symptom duration.
Main highlights

Comprehensive Flu Symptom Relief
Oscillococcinum helps relieve fatigue, headache, body aches, chills, and fever safely for ages 2 and up.

Ideal for Early Flu Onset
Best used at the first sign of flu-like symptoms to reduce duration and severity.

Customer Praised Quick Dissolving
Sweet-tasting pellets dissolve easily under the tongue, praised for convenience.
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9.6

Exceptional

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3

Vicks
VICKS DayQuil & NyQuil SEVERE Co-Pack, Cold & Flu Medicine, Powerful Relief for Headache, Fever, Sore Throat, Minor Aches & Pains, Congestion, Sinus Pressure, Stuffy Nose, and Cough, 48 LiquiCaps

8.9 Flavor

8.7 simple to consume

8.2 worth the money

Why we love it

Effective 9-symptom relief, day and night.

Fast-acting formula for quick symptom relief.

Trusted brand with a long history.
Main highlights

Powerful 9-Symptom Relief
Vicks DayQuil and NyQuil Severe provide maximum strength relief for 9 common cold and flu symptoms.

Day and Night Use
Ideal for daytime use with DayQuil's non-drowsy formula and nighttime relief with NyQuil for restful sleep.

Quick Symptom Relief
Customers praise the fast-acting nature, clearing congestion in 10-15 minutes.
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9.4

Excellent

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4

Amazon Basic Care
Amazon Basic Care Vapor Ice Day and Night Severe Cold and Flu Relief Caplets, Maximum Strength Medicine, Combo Pack, 48 Count

9.3 simple to consume

9.1 worth the money

8.7 Flavor

Why we love it

Effective day and night relief.

Great value for money.

Fast-acting formula.
Main highlights

Maximum Strength Multi-Symptom Relief
Provides around-the-clock relief for cold and flu symptoms with a combination of daytime and nighttime caplets.

Ideal for Families and Busy Individuals
Perfect for those needing effective relief during the day and restful sleep at night.

Highly Praised Nighttime Formula
Customers appreciate the nighttime caplets for aiding sleep and symptom relief.
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9.2

Excellent

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5

Mucinex
Mucinex Fast-Max Liquid Gels for Day/Night Cold and Flu, 24 Count

25% Off

9.7 quality of ingredients

9.5 pain management

8.0 simple to consume

Why we love it

Fast relief from multiple symptoms.

Day and night formulas included.

Highly trusted brand.
Main highlights

Multi-Symptom Relief Efficiency
Provides fast, powerful relief for 9 cold and flu symptoms.

Ideal for Day and Night Use
Designed for comprehensive symptom management, both day and night.

Quick Symptom Relief Praised
Customers appreciate the fast-acting relief, often within two doses.
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9.1

Excellent

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6

Amazon Basic Care
Amazon Basic Care Daytime Cold and Flu Relief Liquid Caps Softgel, Non-Drowsy Cold Medicine, Relief of Pain, Fever, Cough, Sore Throat, Nasal Congestion, 48 Count

9.3 simple to consume

9.3 Flavor

9.1 worth the money

Why we love it

Non-drowsy formula for daytime use.

Effective multi-symptom cold relief.

Affordable alternative to name brands.
Main highlights

Multi-Symptom Relief and Non-Drowsy
Provides relief from headache, fever, sore throat, nasal congestion, and cough without causing drowsiness.

Ideal for Daytime Cold and Flu Relief
Best used during the day for managing cold and flu symptoms while staying active.

Quick and Effective Relief Praised
Customers appreciate the fast-acting relief and easy-to-swallow softgels.
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8.9

Very Good

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7

Tylenol
Tylenol Cold + Flu Severe Medicine Caplets for Cold & Flu Symptom Relief, Fever Reducer, Pain Reliever, Cough Suppressant, Nasal Decongestant & Expectorant with Acetaminophen, 2 pks of 24 ct ea, 48 ct

28% Off

Why we love it

Effective multi-symptom relief.

Suitable for ages 12 and up.

Fast, reliable delivery.
Main highlights

Comprehensive Symptom Relief
Tylenol Cold + Flu Severe Medicine Caplets provide multi-symptom relief for fever, aches, sore throat, congestion, and cough.

Ideal for Cold and Flu Season
Perfect for adults and children 12+ needing relief from severe cold and flu symptoms.

Fast Delivery Praised by Customers
Customers appreciate the quick delivery, often arriving earlier than expected, which is a lifesaver during illness.
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8.8

Very Good

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8

Mucinex
Mucinex Maximum Strength Fast-Max Cold & Flu and Nightshift, All-in-One Multi Symptom Relief Liquid, 6 Fl Oz - 2 Count (Pack of 1)

8.7 Flavor

8.7 worth the money

8.0 Simple to use

Why we love it

Fast-acting relief for cold symptoms.

Convenient day and night formulas.

Pleasant grape flavor praised by users.
Main highlights

Powerful Multi-Symptom Relief
Provides maximum strength relief for cold and flu symptoms, including sore throat, cough, and congestion.

Ideal for Severe Cold and Flu
Perfect for adults experiencing severe cold and flu symptoms, day or night.

Highly Effective Liquid Formula
Customers praise the liquid formula for its fast-acting relief and pleasant grape flavor.
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8.7

Very Good

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9

Amazon Basic Care
Amazon Basic Care Daytime and Nighttime Max Strength Severe Cold and Flu Relief Medicine, Combo Pack, Liquid Medication for Day and Night, Original and Berry, 24 fl oz (Pack of 1)

9.1 worth the money

9.1 Comfort

8.4 Flavor

Why we love it

Provides relief from severe cold and flu symptoms around the clock

Contains maximum strength ingredients for daytime and nighttime relief

Helps you power through the day and rest at night
Main highlights

NIGHTTIME RELIEF: Nighttime Severe cold medicine contains acetaminophen (pain reliever/fever reducer), dextromethorphan HBr (cough suppressant), doxylamine succinate (antihistamine) and phenylephrine HCl (nasal decongestant) so you can rest at night
MAXIMUM STRENGTH: Get maximum strength relief for your severe cold and flu symptoms
DAYTIME RELIEF: Daytime Severe cold medicine contains acetaminophen (pain reliever/fever reducer), dextromethorphan HBr (cough suppressant), guaifenesin (expectorant) and phenylephrine HCl (nasal decongestant) to help you power through the day
AROUND THE CLOCK: Relieve symptoms during the day and at night while you sleep with Amazon Basic Care Daytime and Nighttime Severe Cold and Flu Relief
ACTIVE INGREDIENTS: Compare this daytime and nighttime cold medicine to Vicks DayQuil Severe and Vicks NyQuil Severe active ingredients
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8.5

Good

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10

Vicks
VICKS DayQuil & NyQuil SEVERE Honey Flavor Co-Pack, Cold & Flu Medicine, RelievesHeadache, Fever, Sore Throat, Minor Aches & Pains, Nasal Congestion, Sinus Pressure, Stuffy Nose, and Cough, 2x12oz

8.0 worth the money

8.0 Flavor

Why we love it

Effective relief for cold and flu symptoms.

Honey flavor improves taste experience.

Day and night formulas for 24-hour relief.
Main highlights

Maximum Strength Relief
Provides powerful relief for 9 cold and flu symptoms with real honey flavor.

Day and Night Use
Ideal for treating symptoms any time with non-drowsy DayQuil and restful NyQuil.

Honey Flavor Praised
Most users appreciate the honey flavor for better taste compared to traditional options.
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8.3

Good

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Cold And Flus of 2025

1

Vicks DayQuil & NyQuil Ultra Concentrated Liquicaps Co-Pack, Cold & Flu Medicine, Powerful Multi-Symptom Daytime & Nighttime Relief for Headache, Fever, Sore Throat, Minor Aches & Pains, & Cough, 96ct

2

Boiron Oscillococcinum For Relief From Flu-Like Symptoms Of Body Aches, Headache, Fever, Chills, And Fatigue - 30 Count

Why we love it

3

VICKS DayQuil & NyQuil SEVERE Co-Pack, Cold & Flu Medicine, Powerful Relief for Headache, Fever, Sore Throat, Minor Aches & Pains, Congestion, Sinus Pressure, Stuffy Nose, and Cough, 48 LiquiCaps

Why we love it

4

Amazon Basic Care Vapor Ice Day and Night Severe Cold and Flu Relief Caplets, Maximum Strength Medicine, Combo Pack, 48 Count

Why we love it

5

Mucinex Fast-Max Liquid Gels for Day/Night Cold and Flu, 24 Count

Why we love it

6

Amazon Basic Care Daytime Cold and Flu Relief Liquid Caps Softgel, Non-Drowsy Cold Medicine, Relief of Pain, Fever, Cough, Sore Throat, Nasal Congestion, 48 Count

Why we love it

7

Tylenol Cold + Flu Severe Medicine Caplets for Cold & Flu Symptom Relief, Fever Reducer, Pain Reliever, Cough Suppressant, Nasal Decongestant & Expectorant with Acetaminophen, 2 pks of 24 ct ea, 48 ct

Why we love it

8

Mucinex Maximum Strength Fast-Max Cold & Flu and Nightshift, All-in-One Multi Symptom Relief Liquid, 6 Fl Oz - 2 Count (Pack of 1)

Why we love it

9

Amazon Basic Care Daytime and Nighttime Max Strength Severe Cold and Flu Relief Medicine, Combo Pack, Liquid Medication for Day and Night, Original and Berry, 24 fl oz (Pack of 1)

Why we love it

10

VICKS DayQuil & NyQuil SEVERE Honey Flavor Co-Pack, Cold & Flu Medicine, RelievesHeadache, Fever, Sore Throat, Minor Aches & Pains, Nasal Congestion, Sinus Pressure, Stuffy Nose, and Cough, 2x12oz

Why we love it

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