Our rankings are cleverly generated from the algorithmic analysis of thousands of customer reviews about products, brands, merchant’s customer service levels, popularity trends, and more. The rankings reflect our opinion and should be a good starting point for shopping. By purchasing the products we rank, you’ll get the lowest price we found while we may receive a commission at no cost to you, which will help us continue to provide you with value.
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Acetaminophens of 2025
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- Health care
- Over-the-counter medication
- Pain relievers
- Non-aspirin
- Acetaminophen
- Best Choice
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TIME-CAP LABS, INC.TIME-CAP LABS, INC. Timely Acetaminophen 650 MG - 400 Caplets - Extended Release - Joint Pain Relief, Pain Reliever & Arthritis Pain Relief
Main highlights-
Effective Pain Relief
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Ideal for Family Use
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Cost-Effective Solution
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- Value for Money
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Amazon Basic CareAmazon Basic Care Acetaminophen Extended-Release Tablets, 650 mg, Arthritis Pain, 400 Count
Main highlights-
Extended-Release Pain Relief
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Ideal for Arthritis and Aches
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Value and Effectiveness
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Amazon Basic CareAmazon Basic Care - Extra Strength Acetaminophen Caplet 500 mg, 100 Count ( 50 pouches of 2 caplets )
Main highlights-
Extra Strength Pain Relief
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Convenient Travel Packs for On-the-Go
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Affordable and Effective
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4
TylenolTylenol Extra Strength Acetaminophen Rapid Release Gels, Extra Strength Pain Reliever & Fever Reducer, Gelcaps with Laser-Drilled Holes, 500 mg Acetaminophen, 100 ct
24% OffMain highlights-
Fast Acting Relief
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Ideal for Adults and Teens
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Highly Praised Effectiveness
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Amazon Basic CareAmazon Basic Care Rapid Release Acetaminophen Caplets 500 mg, Extra Strength Pain Reliever and Fever Reducer, 400 Count
Main highlights-
Rapid Pain Relief and Fever Reduction
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Ideal for Headaches and Muscle Aches
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Highly Praised for Effectiveness
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See Today’s Deals & Prices
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GoodSenseGoodSense Extra Strength Pain Relief, Acetaminophen Caplets, 500 mg, 500 Count
Main highlights-
Effective Pain Relief and Fever Reduction
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Ideal for Families and Frequent Users
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High Value for Money
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TylenolTylenol Extra Strength Caplets with 500 mg Acetaminophen, Pain Reliever and Fever Reducer for Headache, Backache, Toothache & Minor Arthritis Pain Relief, 100 Count
Main highlights-
Effective Pain Relief and Fever Reduction
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Versatile Use for Common Ailments
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Convenient and Trusted by Customers
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TylenolTylenol 8 Hour Acetaminophen 650 mg Extended Release Caplets, Fast Acting Bi-Layer Design, Quick & Long Lasting Pain Relief for Muscle, Joint, Back & Arthritis Aches, Fever Reducer, 100 Count
24% OffMain highlights-
Extended_Release for Long-Lasting Relief
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Ideal for Muscle and Joint Pain
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Highly Recommended for Pain Relief
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Similar products on Amazon
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Amazon Basic Care Extra Strength Pain Relief, Acetaminophen Caplets, 500 mg, 200 Count (Packaging may vary)
ACTIVE INGREDIENT: Amazon Basic Care Extra Strength Pain Relief's active ingredient is Acetaminophen, 500 mg, which compares to the active ingredient of Extra Strength Tylenol CapletsAmazon Basic Care Extra Strength Pain Relief, Acetaminophen Caplets, 500 mg, temporarily relieves minor aches and pains due to: the common cold, headache, backache, minor pain of arthritis, toothache, muscular aches, and premenstrual and menstrual cramps also temporarily reduces fever$6.27
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Tylenol Regular Strength Tablets with 325 mg of Acetaminophen, Fever Reducer & Pain Reliever for Headache, Backache, Muscle Aches, Joint Pain & Menstrual Cramps, 100 ct
100-count bottle of Tylenol Regular Strength Tablets with acetaminophen to provide temporary pain relief of minor aches and pains and help reduce fever$6.18
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Amazon Basic Care Acetaminophen Extended-Release Tablets, 650 mg, 100 Count (Packaging may vary)
ACTIVE INGREDIENT: The active ingredient is acetaminophen 650 mg, a pain reliever/fever reducer; compare to the active ingredient of Tylenol 8HR$9.35
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Tylenol 8HR Arthritis Pain Relief Caplets, 650 mg Acetaminophen for Minor Arthritis & Joint Pain, Fever Reducer, Extended Release, Gentle on Stomach, FSA or HSA Eligible, 100 ct
Arthritis pain relief: Tylenol 8HR Arthritis Pain Caplets contain 650mg of acetaminophen; The extended release formula provides fast-acting, long-lasting relief for minor arthritis and joint pain in hands, wrists, knees, ankles, elbows, and feet$12.47
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HealthA2Z® Extra Strength Pain Relief | Acetaminophen 500mg | Contains No Aspirin | Fever Reducer | Pain Reliever (500 Count (Pack of 1))
$11.99
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Compare to Tylenol Arthritis Pain Active Ingredient. - Member's Mark - Arthritis Pain Reliever, Extended Release, Acetaminophen 650 mg, 400 CapletsQ
Compare to Tylenol Arthritis Pain active ingredient. - Member's Mark - Arthritis Pain Reliever, Extended Release, Acetaminophen 650 mg, 400 CapletsQ$23.90
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GoodSense Extra Strength Acetaminophen Caplets 500 mg, Pain Reliever and Fever Reducer, Easy Open Cap, 100 Count
ACTIVE INGREDIENT: GoodSense Extra Strength Acetaminophen Caplets 500 mg's active ingredient is acetaminophen 500 mg. Compare to the active ingredient of Extra Strength Tylenol Caplets.$9.71
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Globe Extra Strength Acetaminophen Tablets 500 mg, Pain Reliever and Fever Reducer, Gentle on Stomach, for Arthritis Pain, Backache Pain and More, 50 Packets of 2 Tablets Each, 100 Count
* WHATS INSIDE: Globe Extra Strength Acetaminophen Tablets 500 mg's active ingredient is acetaminophen 500 mg. Compared to the active ingredient of Leading Name Brands Extra Strength Tablets,$7.99
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HealthA2Z® Extra Strength Pain Relief PM| Acetaminophen 500mg | Diphenhydramine 25mg | Pain Reliever & Nighttime Sleep Aid | (365 Count (Pack of 1))
500 mg Acetaminophen, a proven pain reliever, helps relieve muscle, joint, headache, and arthritis pain quickly.$14.95
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Amazon Basic Care Children's Acetaminophen 160 mg per 5 mL Oral Suspension, Grape Flavor, Pain Reliever and Fever Reducer for Headache, Sore Throat and Toothache, 4 fl oz (Pack of 1)
ACTIVE INGREDIENT: Amazon Basic Care Children's Acetaminophen 160 mg per 5 mL Oral Suspension, Grape Flavor, contains acetaminophen 160 mg per 5 mL. Compare to the active ingredient in Children's Tylenol Oral Suspension$5.77